Grapefruit cocktails offer a zesty twist to your drink menu. These citrus-based beverages blend tart and sweet flavors for a refreshing experience. From classic recipes to modern mixes, there’s a grapefruit drink for every taste.
You can enjoy grapefruit cocktails year-round, but they’re especially popular in warm weather. These drinks often feature vodka, tequila, or gin as the base spirit. Some recipes add extra ingredients like honey or herbs to create unique flavor profiles. Whether you prefer a simple two-ingredient mix or a more complex concoction, grapefruit cocktails are sure to brighten your day.

1. Grapefruit Margarita
The Grapefruit Margarita is a zesty twist on the classic cocktail. It combines tequila, grapefruit juice, and lime juice for a refreshing drink.
To make one, you’ll need tequila, fresh grapefruit juice, lime juice, and simple syrup. Shake these ingredients with ice in a cocktail shaker.
Rim your glass with salt or tajín for extra flavor. Pour the mixture into the glass over ice. Garnish with a grapefruit wedge if you like.
This cocktail is perfect for sunny days or when you want a tangy, citrusy drink. The grapefruit adds a nice bitter note to balance the sweetness.

2. Salty Dog Grapefruit Cocktail
The Salty Dog is a refreshing grapefruit cocktail with a salty twist. It’s made with vodka or gin, fresh grapefruit juice, and a salted rim.
To make one, rim a highball glass with salt. Mix 4 ounces of grapefruit juice with 2 ounces of vodka or gin. Pour over ice in the salted glass.
You can adjust the sweetness by adding simple syrup to taste. For extra flavor, try mixing grapefruit zest into the salt rim.
This drink is perfect for hot summer days. You can easily make a big batch for parties by multiplying the recipe.

3. Grapefruit Negroni
The Grapefruit Negroni puts a citrusy twist on the classic Italian cocktail. You’ll need gin, sweet vermouth, Campari, and fresh grapefruit juice.
To make it, squeeze grapefruit segments into a shaker. Add 1 1/2 ounces gin, 1 ounce sweet vermouth, and 1/2 ounce Campari. Shake well with ice until chilled.
Strain the mixture into a rocks glass over a large ice cube. Garnish with a wide strip of grapefruit peel for an extra burst of citrus aroma.
This refreshing drink balances the bitterness of Campari with the tart sweetness of grapefruit. It’s perfect for sipping on warm evenings or as an aperitif before dinner.

4. Paloma
The Paloma is a refreshing Mexican cocktail that combines tequila and grapefruit. It’s easy to make and perfect for warm days.
To create a Paloma, you’ll need tequila, grapefruit juice, lime juice, and soda water. Some recipes use grapefruit soda instead of juice and soda water.
Rim a glass with salt for extra flavor. Mix the ingredients over ice and stir gently. Garnish with a grapefruit wedge or lime slice.
For a spicy twist, add a dash of chili powder to the salt rim. You can also use mezcal instead of tequila for a smoky variation.

5. Grapefruit Mimosa
A grapefruit mimosa is a refreshing twist on the classic brunch cocktail. You’ll need freshly squeezed grapefruit juice and chilled sparkling wine.
Pour equal parts grapefruit juice and sparkling wine into a champagne flute. For extra flavor, add a splash of elderflower liqueur.
You can garnish your drink with a grapefruit wedge or twist. To make it fancier, rim the glass with sugar before pouring.
This cocktail is perfect for brunch or as a light, citrusy aperitif. You can easily adjust the ratios to suit your taste preferences.

6. Greyhound
The Greyhound is a simple yet refreshing cocktail. It combines grapefruit juice with vodka or gin. This classic drink is perfect for warm days or anytime you crave a tart, citrusy beverage.
To make a Greyhound, mix 2 ounces of vodka or gin with 4 ounces of grapefruit juice. Pour over ice in a highball glass. Stir gently and enjoy.
For added flavor, try using fresh-squeezed pink grapefruit juice. You can also rim the glass with salt to create a Salty Dog variation. This adds a savory touch to each sip.
Experiment with different spirits or add a splash of soda for a bubbly twist. The Greyhound’s versatility makes it a popular choice for cocktail lovers.

7. Grapefruit Basil Gin Fizz
The Grapefruit Basil Gin Fizz is a tasty twist on the classic gin fizz. It combines gin, fresh grapefruit juice, and muddled basil for a unique flavor.
To make this drink, you’ll need gin, grapefruit juice, basil leaves, and tonic water. Muddle the basil in a glass, then add ice, gin, and grapefruit juice. Top it off with tonic water for some fizz.
This cocktail is perfect for summer sipping. The grapefruit adds a tart kick, while the basil brings a fresh, herbal note. It’s a light and refreshing choice for warm days.
You can adjust the sweetness by adding a bit of simple syrup if you prefer. Garnish with a grapefruit slice and basil sprig for a pretty presentation.

8. Sparkling Grapefruit Rosemary Cocktail
This refreshing drink combines the tartness of grapefruit with the aromatic touch of rosemary. To make it, you’ll need grapefruit juice, rosemary-infused simple syrup, and sparkling water.
Start by making the rosemary syrup. Mix sugar and water in a pan, heat until dissolved, then add fresh rosemary sprigs. Let it cool and strain.
In a glass, combine grapefruit juice with the rosemary syrup. Add ice and top with sparkling water. Stir gently to mix.
Garnish your cocktail with a slice of grapefruit and a sprig of fresh rosemary. This drink is perfect for warm summer days or as a festive option at parties.

9. Grapefruit Martini
This twist on a classic martini adds a zesty grapefruit flavor. You’ll need vodka, grapefruit juice, and vermouth. Mix these ingredients in a shaker with ice.
Shake well and strain into a chilled martini glass. For extra flair, add a grapefruit twist or slice as a garnish.
The Grapefruit Martini is tart and refreshing. It’s perfect for sipping on warm evenings or serving at parties. You can adjust the sweetness by adding a splash of simple syrup if desired.

10. Grapefruit Sangria
Grapefruit sangria is a refreshing twist on the classic Spanish punch. You’ll love this citrusy drink on hot summer days.
To make it, mix white wine with fresh grapefruit juice and slices. Add a splash of grapefruit liqueur for extra flavor. Throw in some strawberries or peaches for sweetness.
For a bubbly version, use rosé wine and top with sparkling water. Chill the sangria before serving to let the flavors blend.
Serve over ice in large glasses. This crowd-pleasing drink is perfect for backyard parties or relaxing on the patio after work.

11. Grapefruit Whiskey Sour
You’ll love this zesty twist on a classic cocktail. The Grapefruit Whiskey Sour combines the tartness of grapefruit with the warmth of whiskey.
Mix fresh grapefruit juice, whiskey, and simple syrup in a shaker with ice. Shake well and strain into a glass filled with ice.
For extra flavor, add a dash of bitters. Garnish with a grapefruit wedge or twist. You can use bourbon or rye whiskey based on your taste preference.
This drink balances sweet and sour notes perfectly. It’s refreshing and strong, making it great for sipping on warm evenings.

12. Grapefruit Mojito
The Grapefruit Mojito puts a zesty twist on the classic Cuban cocktail. You’ll love this refreshing drink on a hot summer day.
To make it, muddle mint leaves, lime juice, and simple syrup in a shaker. Add grapefruit juice and white rum, then shake with ice.
Strain the mixture into a glass filled with ice. Top it off with club soda for some fizz. Garnish with a grapefruit wedge and mint sprig.
This cocktail balances sweet, tart, and minty flavors. The grapefruit adds a bright, citrusy kick that pairs well with the rum and mint.
The History of Grapefruit Cocktails
Grapefruit cocktails have a rich and fascinating history. These zesty drinks have evolved from humble beginnings to become beloved classics in bars worldwide.
Origin of Grapefruit Usage in Drinks
Grapefruit first appeared in cocktails in the early 20th century. Bartenders discovered its tart flavor could balance sweet and strong spirits. The fruit gained popularity in the 1920s during Prohibition.
Many believe grapefruit cocktails originated in the Caribbean. Sailors and travelers brought the fruit to new shores. Soon, bartenders experimented with local spirits and grapefruit juice.
One early grapefruit cocktail was the Paloma. This Mexican drink mixed tequila with grapefruit soda. It became a hit and spread to other countries.
Evolution of Grapefruit Cocktails
As time passed, more grapefruit cocktails emerged. The 1930s saw the creation of the Hemingway Daiquiri. This drink used grapefruit juice to cut the sweetness of maraschino liqueur.
The 1950s brought the Greyhound, a simple mix of vodka and grapefruit juice. Later, the addition of salt created the Salty Dog variant.
In recent years, craft cocktail bars have embraced grapefruit. They’ve created new drinks and updated classics. Fresh-squeezed juice and grapefruit bitters are now common ingredients.
Today, you can find grapefruit in a wide range of cocktails. From refreshing summer sippers to complex spirit-forward drinks, grapefruit continues to shine.
Health Benefits of Grapefruit in Cocktails
Grapefruit adds more than just a tangy flavor to cocktails. This citrus fruit packs a nutritional punch and may offer some health perks when enjoyed in moderation.
Nutritional Value of Grapefruit
Grapefruit is low in calories but high in nutrients. A half grapefruit contains:
- About 50 calories
- 2 grams of fiber
- 64% of your daily vitamin C needs
- Small amounts of vitamins A, B6, and potassium
It also has antioxidants like lycopene and beta-carotene. These help protect your cells from damage.
When you add grapefruit juice to cocktails, you get some of these nutrients. Keep in mind that alcohol can affect how your body uses vitamins and minerals.
Potential Health Benefits
Grapefruit may boost your health in a few ways:
- Heart health: The fiber and potassium in grapefruit support heart function.
- Weight management: Its low calorie count can fit into many diets.
- Skin health: Vitamin C helps make collagen, which keeps skin firm.
- Immune system: The vitamin C content may help your body fight off germs.
But don’t rely on grapefruit cocktails for health benefits. Alcohol can cancel out some good effects. Drink these tasty drinks in moderation for best results.